The Krupanidhi Educational Trust was established in 1985 by Prof. Suresh Nagpal an educationist & Prof. Sunil Samson Dhamanigi - philanthropist. Its first concern was to concentrate on pharmacy education for young aspirants of India. The P.U. Courses which form the basic foundation for employment & career opportunities were given prominence in the beginning. The college started Diploma in General Nursing & Midwifery in the year 1992 and Bachelor of Physiotherapy in the year 1995. The College has acquired 20 acres of land with the intention of starting residential School, Hospital, Separate buildings for each department with attached hostels.

The Krupanidhi Pre-University College was started during 1988-89 with the permission and approval of the Government of Karnataka and Directorate of Pre-University Education Department.