Sir Syed College was established in the year 1967 by the Cannore District Muslim Educational Association (Regd). Muslims in Kannur and Kasaragod Districts and Mananthavadi Taluk of the erstwhile Kannur District are educationally backward, and the college was established in Taliparamba mainly to cater to the educational needs of muslims of this region. The college is named after Sir Syed Ahamed Khan to perpetuate the memory of this great leader, who was the pioneer of muslim educational movement in India.

The College has begun as a Junior College in 1967 under the University of Kerala. After the establishment of the new universities in Kerala, the college came under the University of Calicut in 1968, and under the Kannur University in 1996. This College has completed 35 years of its glorious existence.

Sir Syed College is a premier educational institution among the colleges under Kannur University. The College has established its name through the excellent performance and service to the community in particular and the society and nation at large.

The College is situated on a lovely hillock a Karimbam surrounded by an imposing panorama of nature. The calm and serene atmosphere is conductive to physical intellectual and academic pursuits. It is situated 3 KM East of Taliparamba Town and 25 KM North East of Kannur Town.

The College and the hostels are open to students of all casts and creeds. The college is secular in spirit and cosmopolitian in out late