M.O.P. Vaishnav College for Women is committed to the goals of attracting and supporting top caliber women students in the areas of higher education. Dewan Bahadur M.O.Parthasarthy Aiyengar, a leading barrister, visionary, philanthropist of yesteryears was an advocate of women's education. The M.O.P. Charities instituted by him, donated the prime land worth Rs. 25 crores in the heart of Chennai to the college. Sri Vallabhacharya Vidya Sabha, the prominent managing body of D.G. Vaishnav College, in its silver jubilee year, collaborated with Dewan Bahadur M.O. Parthasarthy Aiyengar charities for the establishment of this women's college in 1992, a dream-realization and the result of the determination and sustained efforts of the two trusts. Both these organizations have eminent industrialists, administrators and people committed to the cause of women's education. The infrastructure and administrative expertise is being provided by Sri Vallabhacharya Vidya Sabha. Since its inception the college has recorded a phenomenal continual growth.

Affiliated to the University of Madras, it offers selective career oriented under-graduate and post-graduate courses with premier faculty in a scholarly and research environment. Starting in 1992 with just three courses - B.Com., B.B.A., B.Sc. (Maths.) - the College offers today 12 U.G. and 4 PG. Courses and has a strength of 2743 students thus recording a qualitative and quantitative growth as well. The college offered itself for accreditation in its decennial year and become the first self-financing college to be accredited in the University area. The college has been accredited at four star level by NAAC.

The college also has the distinction of being the youngest college in the country to have been granted Autonomy by University Grants Commision and University of Madras.

The year 2005 saw the colllege, launching up a FM Community Radio (with a frequency of 91.2 Hz), thus creating a history of being the first college in the country to have been granted License by the Government of India. Since 2005, the college also publishes a Newspaper called " The MOP Yuvashakthi" to empower the youth of Chennai.